Chiasma Announces Selecting of John Doyle as Main Economical Officer

George T. Taft

NEEDHAM, Mass., Jan. 19, 2021 (World NEWSWIRE) — Chiasma, Inc. (NASDAQ: CHMA), a industrial-phase biopharmaceutical business using its delivery system technology to create and commercialize oral therapies to make improvements to the lives of sufferers with scarce conditions now taken care of with burdensome and painful injections, as evidenced by its current phased start of MYCAPSSA® as the to start with oral remedy for the treatment of acromegaly, right now declared the selecting of John Doyle as its new Main Economical Officer, productive right now. As formerly noted, Mark Fitzpatrick, Chiasma’s existing President and Principal Financial Officer, will keep on being with the enterprise in a consulting role through June 30, 2021 to assist facilitate a transition of duties to Mr. Doyle. Prior to becoming a member of Chiasma, Mr. Doyle served as Vice President of Finance and Trader Relations at Verastem, Inc.

“It is my enjoyment to welcome John to Chiasma, and I imagine he will make an quick effects as we go on to execute on our U.S. professional launch of MYCAPSSA,” mentioned Raj Kannan, main govt officer of Chiasma. “John delivers an established keep track of history of leadership and good results, and I glance ahead to performing with him in realizing the entire opportunity of Chiasma.”

“I would also like to thank Mark Fitzpatrick for his focused company to Chiasma since becoming a member of the business in 2015. Mark has served in a selection of management roles, which includes as Chief Government Officer, and his many important contributions have enabled our possible potential accomplishment. On behalf of the whole Chiasma crew, I desire Mark the incredibly very best in his long run endeavors,” Mr. Kannan added.

“I was attracted to Chiasma for the reason that of the company’s unwavering determination to carry MYCAPSSA to people in the U.S. and globally, potentially strengthening the lives of people suffering from acromegaly,” mentioned Mr. Doyle. “As an early industrial-stage enterprise, I can not think of a additional exciting time to be a part of the Chiasma crew, and I search ahead to contributing to the company’s commercial and financial objectives.”

Mr. Doyle joins Chiasma from Verastem, Inc., a publicly traded biopharmaceutical company, wherever he most just lately served as Vice President of Finance and Trader Relations. Prior to becoming a member of Verastem in February 2018, he served as Head of Financial Setting up & Assessment at SimpliVity Corp., a application firm that was acquired by Hewlett Packard Enterprises in February 2017. In advance of that, Mr. Doyle was Director of Business enterprise Unit Monetary Planning & Assessment, Early Stage Division, at PAREXEL, a publicly traded pharmaceutical contract investigation group. Earlier in his job, he served in progressively senior financial preparing and investigation roles at Hologic, Inc., a publicly traded provider of healthcare diagnostic, surgical and imaging products and solutions. Mr. Doyle retains a B.S. in finance from the University of Massachusetts.


Sign AND Critical Safety Information and facts

Indication AND Use

MYCAPSSA (octreotide) delayed-launch capsules, for oral use, is a somatostatin analog indicated for extended-expression maintenance treatment in acromegaly sufferers who have responded to and tolerated remedy with octreotide or lanreotide.


Hypersensitivity to octreotide or any of the elements of MYCAPSSA. Anaphylactoid reactions, which includes anaphylactic shock, have been noted in sufferers acquiring octreotide.

Important Security Details

Warnings and Safety measures

MYCAPSSA can bring about complications with the gallbladder. Watch patients periodically. Discontinue if complications of cholelithiasis are suspected.

Blood sugar, thyroid degrees, and vitamin B12 amounts really should be monitored and dealt with accordingly.

Bradycardia, arrhythmia, or conduction abnormalities may possibly arise. Therapy with medicine that have bradycardia outcomes may perhaps have to have to be adjusted.


The most widespread adverse reactions (incidence >10%) are nausea, diarrhea, headache, arthralgia, asthenia, hyperhidrosis, peripheral inflammation, blood glucose improved, vomiting, stomach soreness, dyspepsia, sinusitis, and osteoarthritis.


The next prescription drugs require checking and attainable dose adjustment when applied with MYCAPSSA: cyclosporine, insulin, antidiabetic drugs, calcium channel blockers, beta blockers, lisinopril, digoxin, bromocriptine, and medicine mainly metabolized by CYP3A4. Counsel girls to use an alternate non-hormonal system of contraception or a back-up system when MYCAPSSA is applied with combined oral contraceptives.

Individuals having proton pump inhibitors, H2-receptor antagonists, or antacids concomitantly with MYCAPSSA may possibly call for enhanced dosages of MYCAPSSA.


Suggest premenopausal women of the likely for an unintended being pregnant.

To report SUSPECTED ADVERSE REACTIONS, contact the product information division at 1-844-312-2462 or Food and drug administration at 1-800-Food and drug administration-1088 or and drug

The full Prescribing Information for MYCAPSSA is out there at

About Acromegaly

Acromegaly normally develops when a benign tumor of the pituitary gland produces as well a great deal progress hormone, eventually primary to considerable health troubles. Widespread attributes of acromegaly are facial alterations, intensive headaches, joint discomfort, impaired eyesight and enlargement of the hands, ft, tongue and inner organs. Severe health ailments involved with the progression of acromegaly include things like kind 2 diabetic issues, hypertension, respiratory ailments and cardiac and cerebrovascular ailment. Chiasma estimates that close to 8,000 grownup acromegaly people are chronically treated with somatostatin analog injections in the United States.

About Chiasma

Chiasma is a professional-stage biopharmaceutical firm focused on establishing and commercializing oral therapies to boost the lives of sufferers who deal with difficulties involved with their current therapies for scarce and severe chronic conditions. Utilizing its Tr
ansient Permeability Enhancer (TPE®) technological innovation platform, Chiasma seeks to develop oral remedies that are at present available only as injections. In June 2020, Chiasma acquired Fda acceptance of MYCAPSSA for prolonged-phrase servicing treatment in acromegaly sufferers who have responded to and tolerated therapy with octreotide or lanreotide. MYCAPSSA, the initial and only oral somatostatin analog authorised by the Fda, is out there for industrial sale. Chiasma is headquartered in Needham, MA with a wholly owned subsidiary in Israel. MYCAPSSA, TPE and CHIASMA are registered logos of Chiasma. For additional facts, make sure you take a look at the company’s internet site at

Forward-Hunting Statements

This launch is made up of “forward-on the lookout statements” inside of the meaning of the Non-public Securities Litigation Reform Act of 1995, like, but not confined to, statements with regards to the possible commercial results of MYCAPSSA. This kind of statements are subject matter to quite a few crucial aspects, dangers and uncertainties, several of which are beyond the company’s manage, that might induce true situations or success to differ materially from the company’s existing anticipations. Management’s anticipations and, therefore, any ahead-looking statements in this press launch could be affected by challenges and uncertainties. For a dialogue of these risks and uncertainties, and other crucial factors, any of which could result in the company’s true effects to vary from people contained in the forward-on the lookout statements, see the section entitled “Risk Factors” in Chiasma’s Quarterly Report on Sort 10-Q for the quarter ended September 30, 2020, and in subsequent filings with the Securities and Trade Fee. All facts in this press launch is as of the day of the launch, and Chiasma undertakes no responsibility to update this details except necessary by regulation.


Trader Relations and Company Communications:
Ashley Robinson
LifeSci Advisors, LLC
[email protected]

Media Relations:
Patrick Bursey
LifeSci Communications
[email protected]

Next Post

Eating places be successful in elevating guest sentiment in December

The fourth quarter was not excellent for cafe sales each individual month posted even worse same-retailer sales growth than the earlier thirty day period. By December, exact same-retailer sales advancement fell to -13.3% yr-above-year, the worst month for the business given that July. Identical-retail outlet website traffic progress for the […]